AI Optical Scans Detect Parkinson’s 7 Years in Advance

Groundbreaking Research Reveals Early Prediction Potential


8/23/20232 min read

AI Optical Scans Detect Parkinson’s 7 Years in Advance
AI Optical Scans Detect Parkinson’s 7 Years in Advance

In a remarkable breakthrough, researchers at London's Moorfields Eye Hospital have demonstrated that artificial intelligence (AI) can predict Parkinson's disease up to seven years before an official diagnosis using eye scans. This groundbreaking achievement opens up new possibilities for early intervention and treatment strategies for the disease.

Through the utilization of advanced technology, AI algorithms can analyze high-resolution 3D scans known as optical coherence tomography. This non-invasive and rapid imaging technique delves into the retina with incredible precision, down to a thousandth of a millimeter. The retina serves as a window into the central nervous system, allowing researchers to detect subtle signs and changes that might go unnoticed by human observation.

Previously, identifying Parkinson's disease in its early stages relied heavily on brain imaging, which posed limitations due to its scalability. However, this study explores the association between retinal layer thickness and incident Parkinson's disease, revealing promising results.

Reduced thickness in two optical layers, namely the macular ganglion cell-inner plexiform and the retinal nerve fiber, are strongly correlated with Parkinson's disease development.

Researcher Alastair Denniston, an ophthalmologist at Moorfields Eye Hospital, emphasizes the significance of these findings: "This is the first time anyone has shown these findings several years before diagnosis. We can now detect very early signs of Parkinson's, opening up new possibilities for treatment."

Although the findings do not guarantee the ability to predict an individual's likelihood of developing Parkinson's, they establish a foundation for developing a prescreening tool for those at risk of the disease. Siegfried Wagner, a researcher involved in the study, is amazed by the potential of this technology and envisions its broader applications in the future.

Expanding on the success of AI-driven eye scans, known as "oculomics," this cutting-edge technique holds promise for early detection of various other neurodegenerative diseases and disorders, such as Alzheimer's, multiple sclerosis, and schizophrenia.

By detecting subtle abnormalities before symptoms emerge, individuals could have the opportunity to make lifestyle changes, potentially preventing the onset of certain conditions. Clinicians could also intervene earlier, delaying the impact of life-altering neurodegenerative disorders.


The integration of AI technology and optical scans has revolutionized the detection and prediction of Parkinson's disease. This breakthrough not only provides early warning signs long before an official diagnosis but also presents possibilities for targeted interventions and improved patient outcomes. As further advancements are made, this innovative approach holds great promise in reshaping the landscape of neurodegenerative disease detection and treatment.